Intensive Refinement Kit

SR-9009 SAFETY DATA SHEET
GW0742 SAFETY DATA SHEET
S-23 SAFETY DATA SHEET

The Intensive Refinement Kit is a three-compound combination designed for advanced preclinical investigation of high-potency recomposition models. It pairs two non-androgenic metabolic modulators with one of the most potent SARMs available, forming a research framework that targets aggressive lean tissue augmentation and pronounced fat mass reduction under controlled experimental conditions.

The mechanistic rationale combines REV-ERB and PPARδ activation with high-affinity AR agonism. SR-9009 modulates circadian and oxidative gene expression, GW0742 upregulates fatty acid oxidation and mitochondrial biogenesis, and S-23 delivers potent anabolic signalling with documented reductions in fat mass and minimal fluid retention. The convergence of metabolic, oxidative, and high-potency androgenic pathways produces a research model targeting maximal recomposition outcomes.

Included in this kit:

• 1 × SR-9009 | 100 pellets, 10 mg active compound per pellet
• 1 × GW0742 | 100 pellets, 10 mg active compound per pellet
• 1 × S-23 | 100 pellets, 10 mg active compound per pellet

Total: 300 pellets / 3,000 mg active compound.

Compound roles in this bundle:

SR-9009 (Stenabolic) – REV-ERB agonist supplying the oxidative and circadian metabolism axis, with effects on mitochondrial biogenesis, glucose uptake, and lipid profile modulation.

GW0742 – selective PPARδ agonist contributing the fatty acid oxidation component, modulating gene expression involved in lipid metabolism and endurance-related parameters.

S-23 – high-potency non-steroidal SARM providing aggressive anabolic activity with documented dose-dependent reductions in fat mass and pronounced effects on lean body composition under controlled dietary conditions.

Combined research applications:

• Preclinical models of aggressive recomposition combining oxidative, metabolic, and high-potency anabolic pathways
• Studies of fat mass reduction alongside lean tissue augmentation in murine models
• Investigation of endurance and mitochondrial efficiency under multi-receptor stimulation
• Research into hormonal recovery dynamics following high-potency AR agonist exposure
• Comparative analysis of high-potency versus mild SARM contributions to recomposition outcomes

This kit is positioned as an intensive recomposition combination featuring the most potent SARM in the catalogue alongside two non-androgenic metabolic modulators. Due to S-23’s pronounced suppression of endogenous testosterone and luteinising hormone in animal models, investigators should incorporate appropriate HPG-axis monitoring and consider post-administration endocrine recovery protocols within the experimental design.

⚠ Important Note: This product is supplied strictly for laboratory research use only. It is not approved for human consumption or therapeutic use. Not intended to diagnose, treat, cure, or prevent any disease.