Ostarine UK - SARM

Basic Chemical Structure:

• Molecular Formula: C19H14F3N3O3 [Verify on Pubmed]
• Molecular Weight: 389.33 g/mol
• Classification : SARMS UK 

Structural Features:

• Core Structure: The backbone of Ostarine includes a phenyl ring substituted with a cyano group (CN) and a trifluoromethyl group (CF3), which are critical for its activity and selectivity.
• Linkage: Attached to this phenyl ring is a hydroxymethylpropanamide moiety, a component that plays a crucial role in its binding affinity to the androgen receptor.
• Attachment: The molecule also contains an ether linkage with a phenoxy group, which has additional substituents, enhancing its pharmacokinetic properties such as solubility and stability in biological environments.

Functional Groups and Their Implications:

• Cyano Groups (CN): The presence of cyano groups in Ostarine contributes to its strong binding affinity and selectivity towards androgen receptors. Cyano groups can improve the drug’s stability and its interaction with the target receptor.
• Trifluoromethyl Group (CF3): This group enhances the molecule’s lipophilicity, which can influence its absorption and distribution within the body, potentially increasing its efficacy at target sites.
• Ether and Phenoxy Linkages: These components affect the overall polarity of the molecule, influencing its solubility and its ability to permeate cell membranes.

Stereochemistry:

• Ostarine has specific chiral centers that affect its interaction with androgen receptors. The stereochemistry at these centers can dictate the direction and strength of the binding to the receptor, thereby influencing the drug’s effectiveness and safety profile.

Biological Activity:

The detailed structure of Ostarine allows it to mimic the action of testosterone by binding to androgen receptors selectively, thereby stimulating anabolic activities like muscle growth and bone preservation without many of the side effects associated with conventional anabolic steroids.