GW501516 Pellets (PPARĪ“ Agonist)
GW501516 Pellets are a high-purity research compound engineered for studies in metabolic disorders, cardiovascular health, and exercise physiology. Known for its potent activation of peroxisome proliferator-activated receptor delta (PPARĪ“), GW501516 provides an invaluable tool for exploring pathways in lipid metabolism, glucose regulation, and energy balance.
Product Features and Specifications
- Chemical Formula: C21H18F3NO3S2
- Molecular Weight: 453.5 g/mol
- Form: White to off-white, stable pellets for controlled-release applications.
- Purity: ā„99% by HPLC.
- Solubility: Soluble in DMSO, ethanol, and other organic solvents.
- Storage Conditions: Store at -20Ā°C in a light-protected, moisture-free environment to maintain chemical integrity.
Applications
GW501516 is highly versatile and applicable in the following research areas:
- Metabolic Diseases: Investigating its role in regulating lipid and glucose homeostasis for potential therapies in type 2 diabetes, obesity, and dyslipidemia.
- Cardiovascular Health: Examining its protective effects on endothelial function and prevention of atherosclerosis.
- Exercise Physiology: Exploring its capacity to enhance endurance and skeletal muscle oxidative capacity.
- Chronic Inflammation: Studying anti-inflammatory pathways mediated by PPARĪ“ activation in systemic diseases.
Research Insights
GW501516 has been the subject of extensive preclinical and translational research, showcasing its relevance in metabolic and cardiovascular studies:
-
- Lipid Metabolism: GW501516 has been shown to enhance fatty acid metabolism in skeletal muscle, offering protection against diet-induced obesity and type II diabetes.
- Glucose Regulation: The compound improves insulin sensitivity and reduces glucose levels, making it a potential candidate for managing type 2 diabetes.
- Endurance Enhancement: Studies indicate that GW501516 promotes skeletal muscle fiber type switching, leading to increased physical performance and stamina.
- Cardiovascular Protection: Research suggests that GW501516 mitigates vascular inflammation, supports endothelial integrity, and reduces atherosclerotic plaque formation, demonstrating promise for cardiovascular disease prevention studies.
- Anti-Inflammatory Effects: GW501516 has been found to attenuate pro-inflammatory cytokine release, highlighting its potential in treating chronic inflammatory conditions.
These findings establish GW501516 as a cornerstone in metabolic and cardiovascular research, with broad implications for therapeutic development.
Handling and Safety
- Intended Use: For research use only. Not for human or veterinary applications.
- Safety Precautions: Handle under standard laboratory conditions with appropriate PPE. Avoid direct contact; consult MSDS for detailed handling instructions.
- Documentation: Comprehensive technical sheets and certificates of analysis are available to support regulatory compliance.
Packaging Options
- Available in pellet formulations of 5 mg, 10 mg, and 50 mg for precision dosing in preclinical research.
- Custom packaging and bulk quantities can be tailored to specific research requirements.
Further browsing : SARMS UK
