Buy MK677 Ibutamoren 12.5mg




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MK677 UK
Peptides Water UK

MK677 is a Growth Hormone Scretagogue similar to GHRP.

Although not a SARM, it is often grouped together with Ostarine and the PPAR Agonist Cardarine

Why not checkout our SARM Library to discover more about this compound?

This is research chemical, not for human consumption

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100 / 12.5MG Pellets

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Product name: MK677

Synonyms:  MK677, Ibutamoren

CAS : 159634-47-6

Molecular Formula: C27H36N4O5S

Half-life: 24 hours

Assay/purity:  99%

Appearance/color: White fine powder

Molecular Weight: 528.662 g/mol

We are a UK based company, and we aim to deliver domestic orders within 2 days. EU parcels generally arrive with 5 days, and international parcels can take up to 10 days.

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Our products have a HPLC tested purity of ≥98.0%

You can request a copy of the HPLC reports by contacting us

Manufacture Standards

Our manufacturer complies to the following:

  • GMP
  • ISO 9001
  • CQC China
SARM Certificates

MK677, otherwise known as Ibutamoren is a Growth Hormone secretagogue, it was researched and developed for the pharmacological treatment of various diseases such as MS, obesity ,GH deficiency and osteoporosis.

This hormone signals the pituitary gland to release Growth Hormone, such as other similar compounds like GHRP.

Unlike exogenous HGH administration, MK677 causes a release of natural GH as opposed to synthetic recombinant HGH mimicking the effects. The primary  differences between GHRP and MK677 are the methods of administration, GHRP has a low bioavailability, and must be administered as injection. Ibutamoren is very orally bioavailable, and thus can be effectively orally administered.

MK677 Method of action

MK677 Mechanism of Action

In humans, Growth Hormone is released in pulses, this pulses are either created naturally or can be pharmacologically induced using a Growth Hormone Releasing Hormone such as MK677 or GHRP.

These pulses can be amplified using Mod GRF 1-29.

MK677 Human Use

These hormone has been through various clinical and laboratory studies, and positive effects were found in users.

Preventing disease induced catabolism was of significant important to the development of this drug, for it to be effective and justifiable in the prescription of use in patients suffering from involuntary muscle wastage. Studies have found that subjects who were induced with short term nitrogen wasting showed increased IGF1 and GH levels 7 days after the first dose was administered, reversing the effects of nitrogen wasting.

Trials for obesity found that MK677 did not directly reduce adipose tissue, but increased lean body mass within the subjects, and overall increased the lean body mass, reducing total bodyfat percentage. This was theorised that the calorie surplus consumed by subjects was more efficiently stored in muscle tissue rather than fat cells.

Osteoporosis and MK677 Ibutamoren

MK677 Osteoporosis

Studies conducted on patients suffering from osteoporosis and low levels of body mineral density found that there were noted increasing in bone density, where other factors were controlled. It has been theorised that MK677 can be used to prevent bone injury and disease.

Benefits of MK677 use in patients

Ibutamoren causes higher levels of GH and IGF1, which are proven to improve sleep, energy levels, muscular strength and sense of well being. Higher GH levels are also known to improve skin, reduce the effects of aging and improve hair growth, although not typically prescribed for this use.

Fat loss and MK677 Ibutamoren

MK677 Fat Loss Mechanism

Higher GH levels will generally encourage the body to have a higher disposition to lean tissue and reduced fat tissue, as opposed to a having chronically higher levels on insulin, which promotes storage of nutrients in adipose tissue, and reduces lipolysis (fat loss)