Comparative Analysis

Introduction: Selective estrogen receptor modulators (SERMs) were pioneering drugs that showed scientists it was possible to target hormone receptors with precision. By blocking or activating estrogen receptors in specific tissues, SERMs …

Introduction: Steroidal ligands and nonsteroidal ligands represent two fundamentally different classes of molecules that bind to the androgen receptor. Understanding their differences in chemical structure, ligand binding mechanisms, biological activity, and …