How Long Do SARMs Stay In Your System? What the New Research Says [Case Study]

š§ Key Takeaways
- SARMs can stay in your system from a few days to over 3 weeks, depending on the compound and testing method
- Half-life is not the same as detection window ā full clearance may take multiple half-lives
- RAD-140 and LGD-4033 are among the longest-lasting and most commonly detected
- Most workplace tests do not screen for SARMs, but athletic and military panels may
- Only authorised research use is compliant under UK law ā these compounds are not approved for human consumption
Youāve probably seen this question asked everywhere ā Reddit threads, research forums, even gym locker rooms:
How long do SARMs actually stay in your system?
Whether youāre designing a compliant research protocol, preparing for bloodwork, or just trying to understand metabolic timelines, the answer is more complex than you might think.
Letās break it down by compound, half-life, detection methods, and the latest 2025 data.
š Quick Summary
SARMs can remain detectable in the body for several days to several weeks, depending on the compound, dosage, and testing method.
While half-life gives a rough estimate of clearance, modern detection (especially LC-MS/MS) can identify trace metabolites well beyond the active period.
š§Ŗ What Determines How Long SARMs Stay in Your System?

Several key variables impact detection windows:
- Half-life of the compound
(e.g., RAD-140: ~60 hours, Ostarine: ~24ā36 hours) - Dosage and duration
Higher doses and longer use = longer detection - Metabolism and individual clearance rate
Liver enzymes, hydration, genetics all play a role - Form of administration
Oral solutions vs capsules may slightly alter metabolism - Type of test used
WADA-level urine tests are much more sensitive than home blood panels
Available resource : Half-Life Calculator
ā±ļø Detection Windows by Compound (2025 Estimate)
| Compound | Half-Life (Approx.) | Estimated Detection Window |
|---|---|---|
| Ostarine (MK-2866) | 24ā36 hours | Up to 10ā14 days |
| RAD-140 (Testolone) | ~60 hours | 2ā3 weeks or more |
| LGD-4033 (Ligandrol) | 24ā36 hours | Up to 3 weeks |
| YK-11 | ~6ā10 hours | ~5ā7 days |
| S-23 | ~11ā12 hours | 7ā10 days |
| MK-677 | ~24 hours | ~5ā10 days (non-SARM) |
ā ļø Note: These are estimated for urine testing via LC-MS/MS. Detection in hair or blood could vary.
Updated guidance : SARMs Guide for the UK
𧬠Half-Life ā Clearance Time
A compound is not considered āclearedā just because the effects are gone.
It typically takes 5ā7 half-lives for a compound to leave the body below detectable levels ā and even then, some ultra-sensitive lab equipment can still find metabolites.
For example:
- RAD-140 (60h half-life) ā may require 2ā3 weeks for near-complete clearance
- LGD-4033 has been detected 21 days post-exposure in WADA-tested athletes
š¬ Types of Drug Tests and What They Can Detect
| Test Type | Sensitivity | SARMs Detectable? |
|---|---|---|
| Urine (LC-MS/MS) | Very High | ā Yes |
| Blood Test | Medium | ā ļø Possibly |
| Saliva Test | Low | ā Rarely |
| Hair Test | Extremely High (long window) | ā Some cases |
Most sports testing agencies, like WADA, use LC-MS/MS and can detect SARMs at levels < 1 ng/mL.
Core reading : Can SARMs be detected in a drug test?
š Real Cases: Detection of SARMs

Canadian Centre for Ethics in Sport (CCES), Powerlifting ā 2025
- In JuneāÆ2025, CCES announced a threeāyear sanction for a powerlifter after a competition urine test (from 7 DecemberāÆ2024) showed presence of both RADā140 and another SARM (ostarine). cces.ca
- This illustrates that RADā140 remains detectable in real-world anti-doping analyses (not just experimental labs), and confirms that detection windows can extend beyond the active period of use.
International Powerlifting Federation (IPF) ā 2024
- In May 2024 the IPF publicly sanctioned an athlete who tested positive for RADā140 in a urine sample collected Dec 2023. Powerlifting Federation
- The violation was listed under prohibited āOther Anabolic Agents,ā per the list maintained by World Anti-Doping Agency (WADA). World Anti Doping Agency
- The case proves that RADā140 detection, via approved dopingācontrol labs, is operational and āreal lifeā ā not hypothetical.
PopulationāLevel Study: Swedish Urine Samples (2024)
- In a study published in 2024, a lab analyzing routine urine samples (not just eliteāathlete tests) found SARMs in a non-negligible number of cases. Among 542 male samples, ~4% tested positive for at least one SARM. PubMed
- The most common SARMs identified were LGD-4033, RADā140, and ostarine. Over half of the SARMāpositive samples contained two or more SARMs. PubMed
- The study also found that 40% of SARMāpositive samples also contained classical anabolic-androgenic steroids (AAS), showing āstacking,ā and complicating detection and interpretation. PubMed
- Conclusion: SARM use (including RADā140) isnāt limited to elite athletes ā there is āreal worldā use in the general population, and detection methods are capable of identifying them.
Supplement Contamination & AntiāDoping Sanctions
This highlights a significant risk even for individuals who might not intend to āuse SARMsā ā supplement mislabelling or contamination can trigger positive detection.
There are multiple publicly documented cases where athletes were sanctioned because they tested positive for SARMs present in contaminated dietary supplements ā especially ostarine. sportintegrity
š FAQs (Clear, Click-Worthy Answers)
Are SARMs detectable in blood tests?
Some may be, but blood tests are less sensitive than urine LC-MS/MS. Most standard labs wonāt screen for SARMs unless specifically requested.
How long does RAD-140 stay in your system?
It can remain detectable for up to 2ā3 weeks, depending on dosage, metabolism, and test sensitivity.
Further learning : What is RAD140?
Can SARMs be found in military or workplace drug tests?
Typically no ā unless the test is customised. SARMs are not part of standard 5-panel tests, but elite testing (like for special forces) may include them.
Does the half-life mean itās gone in that time?
No ā it takes 5ā7 half-lives for a compound to clear to non-detectable levels.
What’s the law on SARMs?
Check out our SARMs law Guide
Researcher? Browse our UK SARMs stock here
