Description
SAFETY DATA SHEET
MK-677 HPLC BA34001
MK-677 COA BA34001
Ibutamoren, also known as MK-677, is an orally active, long-acting growth hormone secretagogue that mimics the action of ghrelin by binding to the ghrelin receptor (GHS-R1a) in the brain. This results in a sustained, dose-dependent increase in circulating growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels without significantly affecting cortisol or prolactin secretion. Unlike recombinant GH administration, MK-677 stimulates natural pulsatile release of growth hormone, which may preserve physiological feedback mechanisms and receptor sensitivity.
In clinical and experimental settings, MK-677 has demonstrated the ability to:
- Facilitate increases in fat-free mass and enhances nitrogen balance in preclinical models
- Modulate IGF-1-mediated signaling pathways implicated in skeletal muscle regeneration and tissue repair
- Demonstrate potential to influence bone mineral density parameters, particularly in age-related research contexts
- Affect sleep architecture and REM phase duration, likely through central ghrelin receptor (GHS-R1a) activation
- Alter gene expression and signaling cascades associated with dermal, follicular, and extracellular matrix dynamics in regenerative biology models
Ibutamoren’s oral bioavailability, extended half-life, and minimal suppression of endogenous hormone production make it an attractive candidate for long-term research into GH-related therapies, sarcopenia, and age-associated decline in anabolic hormones.
CAS Number: 159752-10-0
Molecular formula: C27H36N4O5S
Molar mass: 528.7 g/mol
Purity: ≥99% (see HPLC and COA documentation)
Concentration: 10 mg
Half-life: ~24 hours
Storage: 2 years at 20°C
⚠ Important Note: This product is supplied strictly for laboratory research use only. It is not approved for human consumption or therapeutic use. Not intended to diagnose, treat, cure, or prevent any disease.
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Really high quality
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Im impressed with how good and effective MMS/Archem RAD-140 and MK-677 are. They work well and you can rely on them, so its a good choice for research
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Good stuff. Definitely will order from them again.
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I checked the lab reports and they seem legit
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Extremely fast service thank you
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Fast delivery Priced reasonable
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great
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quick delivery
Nick (verified purchase) –
I purchased MK677 about two weeks ago. It arrived quickly. The quality is excellent.
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Getting great results
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It’s definitely one of the best out there. This has to be the purest as I haven’t come across these effects in research from other companies yet.
Albert (verified purchase) –
ok
MML Support (store manager) –
Hi Albert,
Thanks for your feedback — we appreciate you taking the time to leave a review.
If there’s anything we can do to make your experience a 5-star one next time, feel free to let us know!
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I actually like the result
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Accurate description. Conforms to chemical specifications.
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Awesome, worked just as I expected
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Kinda surprised me to be honest quality is on point
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Good
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Valid
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legit 100%
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I’m very impressed with this material. Thank you!
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Best value (price and quality) on the internet
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Works
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so far so good will come back for more
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This product is legit. Great experience.
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strong
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packaging and shipping was great. excellent research results.
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Works well
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Great product. I recommend it!
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Quality products delivered quickly.