AC-262536 / 100 x 5mg

Description

AC-262,536 is a non-steroidal investigational compound classified as a Selective Androgen Receptor Modulator (SARM), originally developed by Acadia Pharmaceuticals for use in preclinical research. It exhibits high binding affinity and partial agonist activity at the androgen receptor (AR), with preferential activation in skeletal muscle and bone tissues, while showing markedly reduced activity in androgen-responsive tissues such as the prostate.

Compared to classical androgens and earlier-generation SARMs, AC-262,536 demonstrates a higher anabolic-to-androgenic activity ratio, making it a relevant molecular tool for examining tissue-selective AR modulation in experimental models. Its pharmacodynamic profile supports its use in studies focused on decoupling anabolic signaling from androgenic effects and endocrine suppression.

In preclinical models, AC-262,536 has shown the ability to:

• Stimulation of skeletal muscle hypertrophy and functional enhancement in androgen-deprived animal models, indicating anabolic activity.
• Preservation of bone microarchitecture and mineral density in preclinical models, suggestive of osteoanabolic potential.
• Limited stimulatory effects on androgen-sensitive tissues such as the prostate, reflecting a favorable anabolic-to-androgenic activity ratio.
• Lack of detectable aromatization or 5α-reduction, indicating minimal interaction with estrogenic or dihydrotestosterone-mediated pathways.
• Partial agonism at the androgen receptor, potentially associated with reduced hypothalamic–pituitary–gonadal (HPG) axis suppression relative to full agonists.

Its relatively mild anabolic profile makes it suitable for baseline anabolic research, studies on androgen receptor modulation, or comparative SARM profiling. However, limited human data is available, and its pharmacokinetics remain under-characterized.

CAS Number: 870888-46-3
Molecular formula: C16H18F3N3O3
Purity: ≥99% (see HPLC and COA documentation)
Concentration: 5 mg
Molar mass: 357.33 g/mol
Half-life: Estimated ~4–6 hours

⚠ Important Note: This product is supplied strictly for laboratory research use only. It is not approved for human consumption or therapeutic use. Not intended to diagnose, treat, cure, or prevent any disease.